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Transcription Factor GATA1 Is Dispensable for Mast Cell Differentiation in Adult Mice

Although previous studies have shown that GATA1 is required for mast cell differentiation, the effects of the complete ablation of GATA1 in mast cells have not been examined. Using conditional Gata1 knockout mice (Gata1(−/y)), we demonstrate here that the complete ablation of GATA1 has a minimal eff...

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Autors principals: Ohneda, Kinuko, Moriguchi, Takashi, Ohmori, Shin'ya, Ishijima, Yasushi, Satoh, Hironori, Philipsen, Sjaak, Yamamoto, Masayuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019035/
https://ncbi.nlm.nih.gov/pubmed/24615013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01524-13
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