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Transcription Factor GATA1 Is Dispensable for Mast Cell Differentiation in Adult Mice

Although previous studies have shown that GATA1 is required for mast cell differentiation, the effects of the complete ablation of GATA1 in mast cells have not been examined. Using conditional Gata1 knockout mice (Gata1(−/y)), we demonstrate here that the complete ablation of GATA1 has a minimal eff...

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Autores principales: Ohneda, Kinuko, Moriguchi, Takashi, Ohmori, Shin'ya, Ishijima, Yasushi, Satoh, Hironori, Philipsen, Sjaak, Yamamoto, Masayuki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019035/
https://ncbi.nlm.nih.gov/pubmed/24615013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01524-13
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