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Protein Kinase C-Dependent Growth-Associated Protein 43 Phosphorylation Regulates Gephyrin Aggregation at Developing GABAergic Synapses

Growth-associated protein 43 (GAP43) is known to regulate axon growth, but whether it also plays a role in synaptogenesis remains unclear. Here, we found that GAP43 regulates the aggregation of gephyrin, a pivotal protein for clustering postsynaptic GABA(A) receptors (GABA(A)Rs), in developing corti...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Wang, Chen-Yu, Lin, Hui-Ching, Song, Yi-Ping, Hsu, Yu-Ting, Lin, Shu-Yu, Hsu, Pei-Chien, Lin, Chun-Hua, Hung, Chia-Chi, Hsu, Min-Ching, Kuo, Yi-Min, Lee, Yih-Jing, Hsu, Chung Y., Lee, Yi-Hsuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405633/
https://ncbi.nlm.nih.gov/pubmed/25755278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01332-14
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