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Palmitoylation of Gephyrin Controls Receptor Clustering and Plasticity of GABAergic Synapses

Postsynaptic scaffolding proteins regulate coordinated neurotransmission by anchoring and clustering receptors and adhesion molecules. Gephyrin is the major instructive molecule at inhibitory synapses, where it clusters glycine as well as major subsets of GABA type A receptors (GABA(A)Rs). Here, we...

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Detalhes bibliográficos
Main Authors: Dejanovic, Borislav, Semtner, Marcus, Ebert, Silvia, Lamkemeyer, Tobias, Neuser, Franziska, Lüscher, Bernhard, Meier, Jochen C., Schwarz, Guenter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099074/
https://ncbi.nlm.nih.gov/pubmed/25025157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001908
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