Palmitoylation of Gephyrin Controls Receptor Clustering and Plasticity of GABAergic Synapses

Postsynaptic scaffolding proteins regulate coordinated neurotransmission by anchoring and clustering receptors and adhesion molecules. Gephyrin is the major instructive molecule at inhibitory synapses, where it clusters glycine as well as major subsets of GABA type A receptors (GABA(A)Rs). Here, we...

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Главные авторы: Dejanovic, Borislav, Semtner, Marcus, Ebert, Silvia, Lamkemeyer, Tobias, Neuser, Franziska, Lüscher, Bernhard, Meier, Jochen C., Schwarz, Guenter
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099074/
https://ncbi.nlm.nih.gov/pubmed/25025157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001908
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