Advanced Glycation End-Products Induce Apoptosis in Pancreatic Islet Endothelial Cells via NF-κB-Activated Cyclooxygenase-2/Prostaglandin E(2) Up-Regulation

Microvascular complications eventually affect nearly all patients with diabetes. Advanced glycation end-products (AGEs) resulting from hyperglycemia are a complex and heterogeneous group of compounds that accumulate in the plasma and tissues in diabetic patients. They are responsible for both endoth...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lan, Kuo-Cheng, Chiu, Chen-Yuan, Kao, Chia-Wei, Huang, Kuo-How, Wang, Ching-Chia, Huang, Kuo-Tong, Tsai, Keh-Sung, Sheu, Meei-Ling, Liu, Shing Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405342/
https://ncbi.nlm.nih.gov/pubmed/25898207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124418
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