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Competition between VanU(G) Repressor and VanR(G) Activator Leads to Rheostatic Control of vanG Vancomycin Resistance Operon Expression

Enterococcus faecalis BM4518 is resistant to vancomycin by synthesis of peptidoglycan precursors ending in D-alanyl-D-serine. In the chromosomal vanG locus, transcription of the resistance genes from the P(YG) resistance promoter is inducible and, upstream from these genes, there is an unusual three...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Depardieu, Florence, Mejean, Vincent, Courvalin, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405338/
https://ncbi.nlm.nih.gov/pubmed/25898178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005170
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