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Structure and Thermodynamics of N(6)-Methyladenosine in RNA: A Spring-Loaded Base Modification

[Image: see text] N(6)-Methyladenosine (m(6)A) modification is hypothesized to control processes such as RNA degradation, localization, and splicing. However, the molecular mechanisms by which this occurs are unclear. Here, we measured structures of an RNA duplex containing m(6)A in the GGACU consen...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Main Authors: Roost, Caroline, Lynch, Stephen R., Batista, Pedro J., Qu, Kun, Chang, Howard Y., Kool, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405242/
https://ncbi.nlm.nih.gov/pubmed/25611135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja513080v
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