DNase I–hypersensitive exons colocalize with promoters and distal regulatory elements

The precise splicing of genes confers an enormous transcriptional complexity to the human genome. The majority of gene splicing occurs cotranscriptionally, permitting epigenetic modifications to affect splicing outcomes. Here we show that select exonic regions are demarcated within the three-dimensi...

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Foilsithe in:Nat Genet
Main Authors: Mercer, Tim R, Edwards, Stacey L, Clark, Michael B, Neph, Shane J, Wang, Hao, Stergachis, Andrew B, John, Sam, Sandstrom, Richard, Li, Guoliang, Sandhu, Kuljeet S, Ruan, Yijun, Nielsen, Lars K, Mattick, John S, Stamatoyannopoulos, John A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405174/
https://ncbi.nlm.nih.gov/pubmed/23793028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2677
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