DNase I–hypersensitive exons colocalize with promoters and distal regulatory elements

The precise splicing of genes confers an enormous transcriptional complexity to the human genome. The majority of gene splicing occurs cotranscriptionally, permitting epigenetic modifications to affect splicing outcomes. Here we show that select exonic regions are demarcated within the three-dimensi...

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Publicat a:Nat Genet
Autors principals: Mercer, Tim R, Edwards, Stacey L, Clark, Michael B, Neph, Shane J, Wang, Hao, Stergachis, Andrew B, John, Sam, Sandstrom, Richard, Li, Guoliang, Sandhu, Kuljeet S, Ruan, Yijun, Nielsen, Lars K, Mattick, John S, Stamatoyannopoulos, John A
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405174/
https://ncbi.nlm.nih.gov/pubmed/23793028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2677
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