DNase I–hypersensitive exons colocalize with promoters and distal regulatory elements

The precise splicing of genes confers an enormous transcriptional complexity to the human genome. The majority of gene splicing occurs cotranscriptionally, permitting epigenetic modifications to affect splicing outcomes. Here we show that select exonic regions are demarcated within the three-dimensi...

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Библиографические подробности
Опубликовано в: :Nat Genet
Главные авторы: Mercer, Tim R, Edwards, Stacey L, Clark, Michael B, Neph, Shane J, Wang, Hao, Stergachis, Andrew B, John, Sam, Sandstrom, Richard, Li, Guoliang, Sandhu, Kuljeet S, Ruan, Yijun, Nielsen, Lars K, Mattick, John S, Stamatoyannopoulos, John A
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405174/
https://ncbi.nlm.nih.gov/pubmed/23793028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2677
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