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Tregs activated by bispecific antibodies: Killers or suppressors?
In recent years, bispecific antibodies (bsAb) have emerged as promising tools for a target-specific redirection of T cells in order to eliminate malignant cells. However, CD3-engaging constructs might also activate T regulatory cells (Tregs) present in the tumor microenvironment. Whether this has de...
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| Publicado no: | Oncoimmunology |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4404924/ https://ncbi.nlm.nih.gov/pubmed/25949920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.994441 |
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