Characterization of the in vivo immune network of IDO, tryptophan metabolism, PD-L1, and CTLA-4 in circulating immune cells in melanoma

In melanoma, both the induction of immunosuppression by tumor cells and the inflammatory antitumor response can induce an upregulation of counter-regulatory mechanisms such as indoleamine 2,3-dioxygenase (IDO), programmed death-ligand 1 (PD-L1) and CTLA-4(+) regulatory T-cells (Tregs) in the tumor m...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Autores principales: Chevolet, I, Speeckaert, R, Schreuer, M, Neyns, B, Krysko, O, Bachert, C, Hennart, B, Allorge, D, van Geel, N, Van Gele, M, Brochez, L
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404886/
https://ncbi.nlm.nih.gov/pubmed/25949897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.982382
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