Reduced NADPH oxidase type 2 activity mediates sleep fragmentation-induced effects on TC1 tumors in mice

The molecular mechanisms underlying how sleep fragmentation (SF) influences cancer growth and progression remain largely elusive. Here, we present evidence that SF reduced ROS production by downregulating gp91(phox) expression and activity in TC1 cell tumor associated macrophages (TAMs), while genet...

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Bibliografische gegevens
Gepubliceerd in:Oncoimmunology
Hoofdauteurs: Zheng, Jiamao, Almendros, Isaac, Wang, Yang, Zhang, Shelley X, Carreras, Alba, Qiao, Zhuanhong, Gozal, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2015
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404846/
https://ncbi.nlm.nih.gov/pubmed/25949873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.976057
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