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Reduced NADPH oxidase type 2 activity mediates sleep fragmentation-induced effects on TC1 tumors in mice

The molecular mechanisms underlying how sleep fragmentation (SF) influences cancer growth and progression remain largely elusive. Here, we present evidence that SF reduced ROS production by downregulating gp91(phox) expression and activity in TC1 cell tumor associated macrophages (TAMs), while genet...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Zheng, Jiamao, Almendros, Isaac, Wang, Yang, Zhang, Shelley X, Carreras, Alba, Qiao, Zhuanhong, Gozal, David
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404846/
https://ncbi.nlm.nih.gov/pubmed/25949873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.976057
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