In vivo profiling reveals immunomodulatory effects of sorafenib and dacarbazine on melanoma

Sorafenib is a multi-kinase inhibitor used alone or in combination with dacarbazine to treat metastasized melanoma. Our study investigated the relationship between metabolic response assessed by PET-CT and global transcriptome changes during sorafenib and dacarbazine therapy in patients with advance...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Urosevic-Maiwald, Mirjana, Barysch, Marjam J, Cheng, Phil F, Karpova, Maria B, Steinert, Hans, Okoniewski, Michal J, Dummer, Reinhard
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404845/
https://ncbi.nlm.nih.gov/pubmed/25949886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.988458
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