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IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors in vivo
A novel approach for the treatment of ovarian cancer includes immunotherapy with genetically engineered T cells targeted to ovarian cancer cell antigens. Using retroviral transduction, T cells can be created that express an artificial T cell receptor (TCR) termed a chimeric antigen receptor (CAR). W...
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| Veröffentlicht in: | Oncoimmunology |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4404840/ https://ncbi.nlm.nih.gov/pubmed/25949921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.994446 |
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