A novel subset of B7-H3(+)CD14(+)HLA-DR(−/low) myeloid-derived suppressor cells are associated with progression of human NSCLC

Myeloid-derived suppressor cells (MDSC) potently inhibit antitumor immune responses, and thereby promoti tumor progression and metastasis. However, the nature of human tumor-infiltrating MDSC remains poorly characterized. Here, we find B7-H3 is exclusively expressed on a subset of intratumoral CD14(...

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Vydáno v:Oncoimmunology
Hlavní autoři: Zhang, Guangbo, Huang, Haitao, Zhu, Yibei, Yu, Gehua, Gao, Xin, Xu, Yunyun, Liu, Cuiping, Hou, Jianquan, Zhang, Xueguang
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404793/
https://ncbi.nlm.nih.gov/pubmed/25949876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2162402X.2014.977164
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