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RhoGDI2 up-regulates P-glycoprotein expression via Rac1 in gastric cancer cells

Multidrug resistance (MDR) is a major clinical obstacle in treatment of gastric cancer. Previously, using 2D electrophoresis-mass spectrometry, we identified RhoGDI2 as a contributor to 5-FU resistance in colon cancer cells, and also confer gastric cancer cells resistance to 5-FU. Here, we reported...

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Bibliografiske detaljer
Udgivet i:Cancer Cell Int
Main Authors: Zheng, Zhong, Liu, Bingya, Wu, Xiaohua
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404694/
https://ncbi.nlm.nih.gov/pubmed/25901126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-015-0190-4
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