Evaluation of public cancer datasets and signatures identifies TP53 mutant signatures with robust prognostic and predictive value

BACKGROUND: Systematic analysis of cancer gene-expression patterns using high-throughput transcriptional profiling technologies has led to the discovery and publication of hundreds of gene-expression signatures. However, few public signature values have been cross-validated over multiple studies for...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Lehmann, Brian David, Ding, Yan, Viox, Daniel Joseph, Jiang, Ming, Zheng, Yi, Liao, Wang, Chen, Xi, Xiang, Wei, Yi, Yajun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404582/
https://ncbi.nlm.nih.gov/pubmed/25886164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1102-7
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