Whole-body organ-level and kidney micro-dosimetric evaluations of (64)Cu-loaded HER2/ErbB2-targeted liposomal doxorubicin ((64)Cu-MM-302) in rodents and primates

BACKGROUND: Features of the tumor microenvironment influence the efficacy of cancer nanotherapeutics. The ability to directly radiolabel nanotherapeutics offers a valuable translational tool to obtain biodistribution and tumor deposition data, testing the hypothesis that the extent of delivery predi...

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Bibliografiske detaljer
Udgivet i:EJNMMI Res
Main Authors: Gaddy, Daniel F, Lee, Helen, Zheng, Jinzi, Jaffray, David A, Wickham, Thomas J, Hendriks, Bart S
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404468/
https://ncbi.nlm.nih.gov/pubmed/25918676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-015-0096-0
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