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Enhancing Protein Expression in HEK-293 Cells by Lowering Culture Temperature

Animal cells and cell lines, such as HEK-293 cells, are commonly cultured at 37°C. These cells are often used to express recombinant proteins. Having a higher expression level or a higher protein yield is generally desirable. As we demonstrate in this study, dropping culture temperature to 33°C, but...

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Pubblicato in:PLoS One
Autori principali: Lin, Chi-Yen, Huang, Zhen, Wen, Wei, Wu, Andrew, Wang, Congzhou, Niu, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404257/
https://ncbi.nlm.nih.gov/pubmed/25893827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123562
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