Validation of gene expression biomarker analysis for biopsy-based clinical trials in Crohn’s disease

BACKGROUND: The ability to measure the expression of pro-inflammatory cytokines from intestinal biopsies in patients with Crohn’s disease in an accurate and reproducible way is critical for proof-of-concept and mechanism-of-action trials; however, the number of biopsies from a segment of the ileum o...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Boland, Brigid S., Boyle, David L., Sandborn, William J., Firestein, Gary S., Levesque, Barrett G., Hillman, Joshua, Zhang, Bing, Proudfoot, James, Eckmann, Lars, Ernst, Peter B., Rivera-Nieves, Jesus, Pola, Suresh, Copur-Dahi, Nedret, Zou, Guangyong, Chang, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404151/
https://ncbi.nlm.nih.gov/pubmed/25545378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000264
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