Validated gene expression biomarker analysis for biopsy-based clinical trials in ulcerative colitis Short title: Inflammatory gene expression in ulcerative colitis

BACKGROUND: Accurate and reproducible measurement of expression of pro-inflammatory cytokines in colonic biopsies from patients with ulcerative colitis (UC) is essential for proof-of-concept and mechanism-of-action studies. Few studies have rigorously established the number of biopsies required for...

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Hauptverfasser: Boland, Brigid S., Boyle, David L., Sandborn, William J., Firestein, Gary S., Levesque, Barrett G., Hillman, Joshua, Zhang, Bing, Proudfoot, James, Eckmann, Lars, Ernst, Peter, Rivera-Nieves, Jesus, Pola, Suresh, Copur-Dahi, Nedret, Chang, John T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143528/
https://ncbi.nlm.nih.gov/pubmed/25041724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.12862
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