MicroRNA-223 is a novel negative regulator of HSP90B1 in CLL

BACKGROUND: MicroRNAs are known to inhibit gene expression by binding to the 3′UTR of the target transcript. Downregulation of miR-223 has been recently reported to have prognostic significance in CLL. However, there is no evidence of the pathogenetic mechanism of this miRNA in CLL patients. METHODS...

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Publicado no:BMC Cancer
Main Authors: Rodríguez-Vicente, Ana E, Quwaider, Dalia, Benito, Rocío, Misiewicz-Krzeminska, Irena, Hernández-Sánchez, María, de Coca, Alfonso García, Fisac, Rosa, Alonso, José-María, Zato, Carolina, de Paz, Juan Francisco, García, Juan Luis, Sarasquete, Ma Eugenia, Hernández, José Ángel, Corchado, Juan M, González, Marcos, Gutiérrez, Norma C, Hernández-Rivas, Jesús-María
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404064/
https://ncbi.nlm.nih.gov/pubmed/25880332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1212-2
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