Restoration of microRNA-214 expression reduces growth of myeloma cells through positive regulation of P53 and inhibition of DNA replication

MicroRNA have been demonstrated to be deregulated in multiple myeloma. We have previously reported that miR-214 is down-regulated in multiple myeloma compared to in normal plasma cells. The functional role of miR-214 in myeloma pathogenesis was explored by transfecting myeloma cell lines with synthe...

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Detalhes bibliográficos
Main Authors: Misiewicz-Krzeminska, Irena, Sarasquete, María E., Quwaider, Dalia, Krzeminski, Patryk, Ticona, Fany V., Paíno, Teresa, Delgado, Manuel, Aires, Andreia, Ocio, Enrique M., García-Sanz, Ramón, San Miguel, Jesús F., Gutiérrez, Norma C.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2013
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3659997/
https://ncbi.nlm.nih.gov/pubmed/23100276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.070011
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