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Human pancreatic cancer stem cells are sensitive to dual inhibition of IGF-IR and ErbB receptors
BACKGROUND: Pancreatic ductal adenocarcinoma is a particularly challenging malignancy characterized by poor responsiveness to conventional chemotherapy. Although this tumor frequently overexpresses or possesses constitutively activated variants of IGF-IR and EGFR/Her-2, clinical trials using inhibit...
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| Опубликовано в: : | BMC Cancer |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403908/ https://ncbi.nlm.nih.gov/pubmed/25886138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1249-2 |
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