The significance of combining VEGFA, FLT1, and KDR expressions in colon cancer patient prognosis and predicting response to bevacizumab

Targeting angiogenesis through inhibition of the vascular endothelial growth factor (VEGF) pathway has been successful in the treatment of late stage colorectal cancer. However, not all patients benefit from inhibition of VEGF. Ras status is a powerful biomarker for response to anti-epidermal growth...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Zhang, Shu-Dong, McCrudden, Cian M, Meng, Chen, Lin, Yao, Kwok, Hang Fai
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2015
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403689/
https://ncbi.nlm.nih.gov/pubmed/25926745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S80518
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