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The prognostic significance of Cdc6 and Cdt1 in breast cancer

DNA replication is a critical step in cell proliferation. Overexpression of MCM2-7 genes correlated with poor prognosis in breast cancer patients. However, the roles of Cdc6 and Cdt1, which work with MCMs to regulate DNA replication, in breast cancers are largely unknown. In the present study, we ha...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mahadevappa, Ravikiran, Neves, Henrique, Yuen, Shun Ming, Bai, Yuchen, McCrudden, Cian M., Yuen, Hiu Fung, Wen, Qing, Zhang, Shu Dong, Kwok, Hang Fai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430515/
https://ncbi.nlm.nih.gov/pubmed/28428557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00998-9
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