Expression of the Novel Hepatitis C Virus Core+1/ARF Protein in the Context of JFH1-Based Replicons

Hepatitis C virus contains a second open reading frame within the core gene, designated core+1/ARF. Here we demonstrate for the first time expression of core+1/ARF protein in the context of a bicistronic JFH1-based replicon and report the production of two isoforms, core+1/L (long) and core+1/S (sho...

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Bibliographic Details
Published in:J Virol
Main Authors: Kotta-Loizou, Ioly, Karakasiliotis, Ioannis, Vassilaki, Niki, Sakellariou, Panagiotis, Bartenschlager, Ralf, Mavromara, Penelope
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403472/
https://ncbi.nlm.nih.gov/pubmed/25694591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02351-14
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