ORF57 Overcomes the Detrimental Sequence Bias of Kaposi's Sarcoma-Associated Herpesvirus Lytic Genes

Kaposi's sarcoma-associated herpesvirus (KSHV) encodes ORF57, which enhances the expression of intronless KSHV genes on multiple posttranscriptional levels. However, it remains elusive how ORF57 recognizes viral RNAs. Here, we demonstrate that ORF57 also increases the expression of the multiple...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Vogt, Carolin, Hackmann, Christian, Rabner, Alona, Koste, Lars, Santag, Susann, Kati, Semra, Mandel-Gutfreund, Yael, Schulz, Thomas F., Bohne, Jens
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403450/
https://ncbi.nlm.nih.gov/pubmed/25694606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03264-14
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