ORF57 Overcomes the Detrimental Sequence Bias of Kaposi's Sarcoma-Associated Herpesvirus Lytic Genes

Kaposi's sarcoma-associated herpesvirus (KSHV) encodes ORF57, which enhances the expression of intronless KSHV genes on multiple posttranscriptional levels. However, it remains elusive how ORF57 recognizes viral RNAs. Here, we demonstrate that ORF57 also increases the expression of the multiple...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Vogt, Carolin, Hackmann, Christian, Rabner, Alona, Koste, Lars, Santag, Susann, Kati, Semra, Mandel-Gutfreund, Yael, Schulz, Thomas F., Bohne, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403450/
https://ncbi.nlm.nih.gov/pubmed/25694606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03264-14
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