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Conserved Molecular Signatures in gp120 Are Associated with the Genetic Bottleneck during Simian Immunodeficiency Virus (SIV), SIV-Human Immunodeficiency Virus (SHIV), and HIV Type 1 (HIV-1) Transmission

Human immunodeficiency virus (HIV) transmission typically results from infection by a single transmitted/founder (T/F) variant. Are T/F variants chosen uniformly at random from the donor pool, or are they selected based on advantageous traits facilitating transmission? Finding evidence for selection...

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Foilsithe in:J Virol
Main Authors: Gonzalez, Mileidy W., DeVico, Anthony L., Lewis, George K., Spouge, John L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403421/
https://ncbi.nlm.nih.gov/pubmed/25589663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03235-14
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