High Secretion of Interferons by Human Plasmacytoid Dendritic Cells upon Recognition of Middle East Respiratory Syndrome Coronavirus

The Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 as the causative agent of a severe respiratory disease with a fatality rate of approximately 30%. The high virulence and mortality rate prompted us to analyze aspects of MERS-CoV pathogenesis, especially its interaction with...

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Publicado en:J Virol
Autores principales: Scheuplein, Vivian A., Seifried, Janna, Malczyk, Anna H., Miller, Lilija, Höcker, Lena, Vergara-Alert, Júlia, Dolnik, Olga, Zielecki, Florian, Becker, Björn, Spreitzer, Ingo, König, Renate, Becker, Stephan, Waibler, Zoe, Mühlebach, Michael D.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403407/
https://ncbi.nlm.nih.gov/pubmed/25609809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03607-14
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