Lentiviral Protein Transfer Vectors Are an Efficient Vaccine Platform and Induce a Strong Antigen-Specific Cytotoxic T Cell Response

To induce and trigger innate and adaptive immune responses, antigen-presenting cells (APCs) take up and process antigens. Retroviral particles are capable of transferring not only genetic information but also foreign cargo proteins when they are genetically fused to viral structural proteins. Here,...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Uhlig, Katharina M., Schülke, Stefan, Scheuplein, Vivian A. M., Malczyk, Anna H., Reusch, Johannes, Kugelmann, Stefanie, Muth, Anke, Koch, Vivian, Hutzler, Stefan, Bodmer, Bianca S., Schambach, Axel, Buchholz, Christian J., Waibler, Zoe, Scheurer, Stephan, Mühlebach, Michael D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524058/
https://ncbi.nlm.nih.gov/pubmed/26085166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00844-15
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