Lentiviral Protein Transfer Vectors Are an Efficient Vaccine Platform and Induce a Strong Antigen-Specific Cytotoxic T Cell Response

To induce and trigger innate and adaptive immune responses, antigen-presenting cells (APCs) take up and process antigens. Retroviral particles are capable of transferring not only genetic information but also foreign cargo proteins when they are genetically fused to viral structural proteins. Here,...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Uhlig, Katharina M., Schülke, Stefan, Scheuplein, Vivian A. M., Malczyk, Anna H., Reusch, Johannes, Kugelmann, Stefanie, Muth, Anke, Koch, Vivian, Hutzler, Stefan, Bodmer, Bianca S., Schambach, Axel, Buchholz, Christian J., Waibler, Zoe, Scheurer, Stephan, Mühlebach, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524058/
https://ncbi.nlm.nih.gov/pubmed/26085166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00844-15
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