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Effective Lethal Mutagenesis of Influenza Virus by Three Nucleoside Analogs

Lethal mutagenesis is a broad-spectrum antiviral strategy that exploits the high mutation rate and low mutational tolerance of many RNA viruses. This approach uses mutagenic drugs to increase viral mutation rates and burden viral populations with mutations that reduce the number of infectious progen...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Pauly, Matthew D., Lauring, Adam S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403394/
https://ncbi.nlm.nih.gov/pubmed/25589650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03483-14
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