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A Host Susceptibility Gene, DR1, Facilitates Influenza A Virus Replication by Suppressing Host Innate Immunity and Enhancing Viral RNA Replication

Influenza A virus (IAV) depends on cellular factors to complete its replication cycle; thus, investigation of the factors utilized by IAV may facilitate antiviral drug development. To this end, a cellular transcriptional repressor, DR1, was identified from a genome-wide RNA interference (RNAi) scree...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Hsu, Shih-Feng, Su, Wen-Chi, Jeng, King-Song, Lai, Michael M. C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403386/
https://ncbi.nlm.nih.gov/pubmed/25589657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03610-14
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