Poly(C)-Binding Protein 2 Interacts with Sequences Required for Viral Replication in the Hepatitis C Virus (HCV) 5′ Untranslated Region and Directs HCV RNA Replication through Circularizing the Viral Genome

Sequences in the 5′ untranslated region (5′UTR) of hepatitis C virus (HCV) RNA is important for modulating both translation and RNA replication. The translation of the HCV genome depends on an internal ribosome entry site (IRES) located within the 341-nucleotide 5′UTR, while RNA replication requires...

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Bibliographic Details
Main Authors: Wang, Linya, Jeng, King-Song, Lai, Michael M. C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3147998/
https://ncbi.nlm.nih.gov/pubmed/21632751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00339-11
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