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Modulation of Flavivirus Population Diversity by RNA Interference

To test the hypothesis that RNA interference (RNAi) imposes diversifying selection on RNA virus genomes, we quantified West Nile virus (WNV) quasispecies diversity after passage in Drosophila cells in which RNAi was left intact, depleted, or stimulated against WNV. As predicted, WNV diversity was si...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Brackney, Doug E., Schirtzinger, Erin E., Harrison, Thomas D., Ebel, Gregory D., Hanley, Kathryn A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403385/
https://ncbi.nlm.nih.gov/pubmed/25631077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02612-14
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