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Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?

Significance: Inflammasomes are multiprotein complexes localized within the cytoplasm of the cell that are responsible for the maturation of proinflammatory cytokines such as interleukin-1β (IL-1β) and IL-18, and the activation of a highly inflammatory form of cell death, pyroptosis. In response to...

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Bibliographic Details
Published in:Antioxid Redox Signal
Main Authors: Abais, Justine M., Xia, Min, Zhang, Yang, Boini, Krishna M., Li, Pin-Lan
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403231/
https://ncbi.nlm.nih.gov/pubmed/25330206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.5994
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