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Large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference

The protein synthesis machineries of two distinct phyla of the Animal kingdom, insects of Arthropoda and mammals of Chordata, have different preferences for how to best encode proteins. Nevertheless, arboviruses (arthropod-borne viruses) are capable of infecting both mammals and insects just like ar...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Shen, Sam H., Stauft, Charles B., Gorbatsevych, Oleksandr, Song, Yutong, Ward, Charles B., Yurovsky, Alisa, Mueller, Steffen, Futcher, Bruce, Wimmer, Eckard
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403163/
https://ncbi.nlm.nih.gov/pubmed/25825721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502864112
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