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AAV-8 Is More Efficient than AAV-9 in Transducing Neonatal Dog Heart
Adeno-associated virus serotype-8 and 9 (AAV-8 and 9) are the leading candidate vectors to test bodywide neonatal muscle gene therapy in large mammals. We have previously shown that systemic injection of 2–2.5×10(14) viral genome (vg) particles/kg of AAV-9 resulted in widespread skeletal muscle gene...
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| Publicado no: | Hum Gene Ther Methods |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403016/ https://ncbi.nlm.nih.gov/pubmed/25763686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2014.128 |
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