Prospective risk of cancer and the influence of tobacco use in carriers of the p16-Leiden germline variant

The p16-Leiden germline variant in the CDKN2A gene is associated with a high risk of melanoma and pancreatic cancer. The aims of this study were to assess the risk of developing other cancers and to determine whether tobacco use would alter cancer risk in carriers of such a variant. We therefore pro...

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Dettagli Bibliografici
Pubblicato in:Eur J Hum Genet
Autori principali: Potjer, Thomas P, Kranenburg, Heidi E, Bergman, Wilma, de Vos tot Nederveen Cappel, Wouter H, van Monsjou, Hester S, Barge-Schaapveld, Daniela Q C M, Vasen, Hans F A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
Soggetti:
Short Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402641/
https://ncbi.nlm.nih.gov/pubmed/25227142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.187
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