Triptolide-Mediated Apoptosis by Suppression of Focal Adhesion Kinase through Extrinsic and Intrinsic Pathways in Human Melanoma Cells

Triptolide (TPL) has been shown to inhibit cell proliferation and induce apoptosis in various human cancer cells; however, the precise mechanism of apoptosis induced by TPL in human melanoma cells has not yet been elucidated. In this study, we investigated the precise mechanism underlying cytocidal...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Kwon, Haw-Young, Kim, Kyoung-Sook, Baik, Ji-Sue, Moon, Hyung-In, Lee, Ji-Won, Kim, Cheorl-Ho, Cho, Young-Su, Jeong, Yong-Kee, Lee, Young-Choon
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402567/
https://ncbi.nlm.nih.gov/pubmed/25945102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/172548
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