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Triptolide-Mediated Apoptosis by Suppression of Focal Adhesion Kinase through Extrinsic and Intrinsic Pathways in Human Melanoma Cells

Triptolide (TPL) has been shown to inhibit cell proliferation and induce apoptosis in various human cancer cells; however, the precise mechanism of apoptosis induced by TPL in human melanoma cells has not yet been elucidated. In this study, we investigated the precise mechanism underlying cytocidal...

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Bibliographische Detailangaben
Veröffentlicht in:Evid Based Complement Alternat Med
Hauptverfasser: Kwon, Haw-Young, Kim, Kyoung-Sook, Baik, Ji-Sue, Moon, Hyung-In, Lee, Ji-Won, Kim, Cheorl-Ho, Cho, Young-Su, Jeong, Yong-Kee, Lee, Young-Choon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402567/
https://ncbi.nlm.nih.gov/pubmed/25945102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/172548
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