Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference

The discovery that the machinery of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 bacterial immune system can be re-purposed to easily create deletions, insertions and replacements in the mammalian genome has revolutionized the field of genome engineering and re-invigor...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Barrangou, Rodolphe, Birmingham, Amanda, Wiemann, Stefan, Beijersbergen, Roderick L., Hornung, Veit, Smith, Anja van Brabant
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Survey and Summary
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402539/
https://ncbi.nlm.nih.gov/pubmed/25800748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv226
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