Activating GNAS and KRAS mutations in gastric foveolar metaplasia, gastric heterotopia, and adenocarcinoma of the duodenum

BACKGROUND: Heterotopic gastric-type epithelium, including gastric foveolar metaplasia (GFM) and gastric heterotopia (GH), is a common finding in duodenal biopsy specimens; however, there is still controversy regarding their histogenetic backgrounds. METHODS: We analysed a total of 177 duodenal lesi...

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Vydáno v:Br J Cancer
Hlavní autoři: Matsubara, A, Ogawa, R, Suzuki, H, Oda, I, Taniguchi, H, Kanai, Y, Kushima, R, Sekine, S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
Genetics and Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402452/
https://ncbi.nlm.nih.gov/pubmed/25867268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.104
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