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Interleukin 23 Produced by Myeloid Dendritic Cells Contributes to T-Cell Dysfunction in HIV Type 1 Infection by Inducing SOCS1 Expression

The mechanism of myeloid dendritic cell (mDC)–mediated impaired T-cell function was investigated during human immunodeficiency virus type 1 (HIV-1) infection. HIV or gp120 were found to inhibit lipopolysaccharide-induced mDC maturation and cause defects in allogeneic T-cell proliferation, interleuki...

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Bibliographische Detailangaben
Veröffentlicht in:J Infect Dis
Hauptverfasser: Garg, Ankita, Rawat, Pratima, Spector, Stephen A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402373/
https://ncbi.nlm.nih.gov/pubmed/25234720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu523
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