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HIV Type 1 gp120–Induced Expansion of Myeloid Derived Suppressor Cells Is Dependent on Interleukin 6 and Suppresses Immunity

Background. Factors responsible for myeloid-derived suppressor cell (MDSC) expansion and T-cell dysfunction during human immunodeficiency virus type 1 (HIV) infection are unknown. This study investigated the role of MDSCs during HIV infection. Methods. Peripheral blood mononuclear cells (PBMCs) were...

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Autori principali: Garg, Ankita, Spector, Stephen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3883171/
https://ncbi.nlm.nih.gov/pubmed/23999600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit469
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