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Senescence of immortal human fibroblasts by the introduction of normal human chromosome 6.

In these studies we show that introduction of a normal human chromosome 6 or 6q can suppress the immortal phenotype of simian virus 40-transformed human fibroblasts (SV/HF). Normal human fibroblasts have a limited life span in culture. Immortal clones of SV/HF displayed nonrandom rearrangements in c...

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Autors principals: Sandhu, A K, Hubbard, K, Kaur, G P, Jha, K K, Ozer, H L, Athwal, R S
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC44023/
https://ncbi.nlm.nih.gov/pubmed/8202516
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